Comparative Evaluation of Postoperative Pain Following Vital Pulpotomy Using Simvastatin versus MTA in Immature Molars: randomized clinical trial

To Compare Postoperative pain after pulpotomy using simvastatin gel (SMG) and MTA.Materials and methods: Eighty immature molars of children aged 6–8 years were selected. Teeth were randomly assigned into two equal groups (40 immature molar per group). In the intervention group, the pulps were capped with freshly prepared SMG of a concentration of 1 μM/L While, immature molars in the control group were treated with MTA (MTA Angelus, Londrina, Brazil). Postoperative pain was measured following vital pulpotomy of the immature teeth using the visual analogue scale (VAS). The pain intensity was measured after 6, 12, 24, 48, 72, and 1 week. The scores were statistically tested to elucidate the difference between the two groups. The level of significance was adjusted to 0.05 (p ≤ 0.05). Over the follow-up period, there was significant difference in postoperative pain intensity was found between the two groups (p ≤ .05), pain intensity was conclusive at 6, 12, 24, 48, 72, and 1 week denoting that the superiority of the SMG over MTA. There was less pain associated with SMG group compared to who’s treated with MTA group.