Comparison Between Mesenchymal Stem Cells Isolated from Bone Marrow, Wharton Jelly in Osteogenic Differentiation
Mesenchymal stem cells (MSC) are multipotent cells that exist in multiple prenatal tissues, such as human bone marrow, umbilical cord, gingiva and dental pulp. These MSC have a significant ability to differentiate into multiple cell lineage such as adipose cells, bone cells, and cartilage cells. To evaluate the most potent source of MSC that can produce the most functional and abundant osteoblast; we performed this study. We compared between two sources of MSC Bone marrow (BM) and umbilical cord (UC) MSC, and tried to measure the quality of induced osteoblast through quantifying the levels of
Comparative Evaluation of Postoperative Pain Following Minimally Invasive Versus Conventional Le Fort I Osteotomy
In this study, we comparation the minimally invasive Le Fort I osteotomy with the conventuals technique regarding the post operative pain. This study is a prospective case-control study including sixteen patients divided into two equal groups: control group underwent conventuals Le Fort I osteotomy, while Study group received a minimally invasive technique. Postoperative pain levels were comparable between groups on D1 and W1; however, the Study Group experienced significantly lower pain at W2, W3, and W4 (P = 0.005, 0.005, and 0.001, respectively). The minimally invasive technique proved more
Copeptin in liver Cirrhosis: A review article
Liver cirrhosis represents the advanced stage of all chronic liver diseases, marked by tissue fibrosis and the formation of irregular structural nodules. Copeptin, a 39-amino-acid glycopeptide with no fully defined physiological role, is co-synthesized with vasopressin, also known as the antidiuretic hormone, and directly reflects vasopressin levels. As an alternative marker for vasopressin, copeptin is both practical and valuable in assessing hemodynamic instability and prognosis in cirrhosis. This study examines the relationship between copeptin and liver cirrhosis, highlighting its potentia
Protective effects of selenium nanoparticles against methotrexate induced gastric toxicity
Methotrexate (MTX) is a commonly used drug for the treatment of many diseases. It is used as immune-modulator drug in the treatment of autoimmune diseases. However, it has many toxic effects on different body organs such as gastrointestinal toxicity, hepatotoxicity, nephrotoxicity, testicular toxicity, neurotoxicity, and hematological toxicity. Gastrointestinal toxicity includes mucositis, diarrhea, and constipation, and can often be a dose-limiting complication, induce cessation of treatment and could be life threatening. Many studies were performed to evaluate effects of natural agents again
Increased B7-H3 Immunostaining is Associated with Muscle Invasiveness in Urinary Bladder Carcinoma
Urinary Bladder carcinoma (UBC) is a worldwide health issue. B7 homolog 3 protein (B7-H3), also known as cluster of differentiation 276 (CD276); it belongs to the B7 family of molecules and regulates the immune system's response to tumours. It is closely linked to the progression, metastasis, recurrence, and other undesirable clinical aspects of tumours, and is widely expressed in urologic tumours as well as other human malignancies as reported by previous studies. Targeting B7-H3 directly on tumour cells is a promising strategy. Such targeting would require knowledge about the amount of recep