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Fa yi xue za zhi

Fa yi xue za zhi

Fa yi xue za zhi (ISSN:1004-5619) is a monthly peer-reviewed scopus-indexed journal from 1997 to Present. The publisher of this journal is the Journal of Forensic Medicine. Fa yi xue za zhi is committed to gathering and disseminating excellent research achievements. Inspiring medical innovation and promoting the Development of Disciplines. Fa yi xue za zhi | FYXZZ welcomes all types of medical journals including General Medicine, pharmacy, biochemistry, psychology, Public health, and so on.

Aim And Scope

Fa yi xue za zhi

Anatomy, Physiology, Biochemistry, Pharmacology, Pathology Forensic medicine, Microbiology, Community Medicine, Otorhinolaryngology, Internal Medicine, General Surgery, Obstetrics and Gynecology, Radiology, Pulmonary Medicine, Dermatology and Venereal diseases, Infectious Diseases, Anaesthesia, Cancer research, Neurosurgery, Orthopedics, Gastroenterology, Neurology, Nephrology, Medical education, Orthopaedics, Paediatrics, Reproduction, Cardiology, Diabetes, Surgery, Nursing, Otolaryngology, Dental, Psychology, Anesthesiology Dermatology, Endocrinology,

Hepatology, Urology, Venereology, Psychiatry, Biotechnology, Pharmacy, ENT, Pharmaceutical Chemistry, Pharmaceutical Analysis, Pharmaceutics, Pulmonology, Pharmacognosy, Pharmaceutical, Phatmaceutical Technology, Biopharmaceutics, Pharmacokinetics Pharmacodynamics, Industrial Pharmacy, Drug Design, Quality Assurance, Drug Regulatory Affairs, Phytochemistry, Drug Delivery Systems, Pharmaceutical Nanotechnology, Pharmaceutical Microbiology, Hospital Pharmacy, Clinical Pharmacy, Pharmacy Practice, Drug Discovery, Drug Metabolism, Toxicology, Clinical Research, Pharmacogenomics, Phrmacoinformatics, Pharmacovigilance<, Life Sciences like Chemistry, Biomedical Sciences, Microbiology,

Immunology, Forensic, Epidemiology, Oncology, Biomedicine, Dentistry, Physiotherapy, Gynaecology, Dermatoepidemiology, Neuroscience, Ophthalmology, Sexology, Osteology, Kinesiology, Angiology/Vascular Medicine, Critical care Medicine, Haematology, Infectious Diseases and Vaccinology, Bariatrics, Pharmacy and Nursing, Pharmacognosy and Phytochemistry, Radiobiology, Clinical immunology, Clinical and Hospital Pharmacy, Cell Biology, Genomics and Proteomics, Healthcare Services, Healthcare Management, Bioinformatics and Biotechnology, Geriatric Medicine,
Scopus Index(2024)

Submission Deadline ( Vol 40 , Issue 02 ) 18 May 2024

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Publish On ( Vol 40 , Issue 02 ) 31 May 2024

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Fa yi xue za zhi

Metabonomics Analysis of Brain Stem Tissue in Rats with Primary Brain Stem Injury Caused Death

To explore the potential biomarkers for the diagnosis of primary brain stem injury (PBSI) by using metabonomics method to observe the changes of metabolites in rats with PBSI caused death. PBSI, non-brain stem brain injury and decapitation rat models were established, and metabolic maps of brain stem were obtained by LC-MS metabonomics method and annotated to the HMDB database. Partial least square-discriminant analysis (PLS-DA) and random forest methods were used to screen potential biomarkers associated with PBSI diagnosis. Eighty-six potential metabolic markers associated with PBSI were

FYXZZ-06-04-2024-1201
Fa yi xue za zhi
Application of Microhaplotypes in Sibling Kinship Testing

To investigate the efficacy of different numbers of microhaplotype (MH) loci and the introduction of different reference samples on the identification of full sibling, half sibling and differentiation between full sibling and half sibling kinships, and to explore the effect of changing mutation rate on sibling testing. First, a family map involving three generations was established, and four full sibling identification models, five half sibling identification models and five models distinguishing full and half siblings were constructed for different reference samples introduced. Based on th

FYXZZ-06-04-2024-1200
Fa yi xue za zhi
Calculation of the Paternity Index for the Alleged Father Related to the Child’s Mother

To derive the paternity index (PI) calculation formula of the alleged father (AF) when the AF is a relative (parent/child, siblings, grandparent/grandchild, uncle/nephew, first cousins) of the child's biological mother. For the case when the AF is related to the child's biological mother, the existence of the relationship in the numerator and denominator hypothesis of PI was considered. The genotype frequency of the AF was calculated by using the frequency formula in which the mother's genotype was considered, while the random male in the denominator was substituted as another r

FYXZZ-06-04-2024-1199
Fa yi xue za zhi
Evaluation of Detection Efficiency for Trio Full Sibling Testing

To study the detection efficiency of trio full sibling with another known full sibling reference added under different number of autosomal STR typing systems. Based on 43 detection systems consisting of 13 to 55 representative autosomal STR loci, 10 000 true families (full sibling group) and 10 000 false families (unrelated individual group) were randomly simulated. The full sibling index (FSI) was calculated based on the method of family reconstruction. The cumulative sibling relationship index (CFSI) of 0.000 1 and 10 000 were used as the evaluation thresholds, and the detection efficienc

FYXZZ-06-04-2024-1198
Fa yi xue za zhi
Application of Familial Y-STR Haplotype Mismatch Tolerance in Genealogy Inference

To provide a guideline for genealogy inference and family lineage investigation through a study of the mismatch tolerance distribution of Y-STR loci in Chinese Han male lineage. Three Han lineages with clear genetic relationships were selected. YFiler Platinum PCR amplification Kit was used to obtain the typing data of 35 Y-STR loci in male samples. The variation of Y-STR haplotypes in generation inheritance and the mismatch tolerance at 1-7 kinship levels were statistically analyzed. Mutations in Y-STR were family-specific with different mutation loci and numbers of mutation in different l

FYXZZ-06-04-2024-1197
Fa yi xue za zhi
Methods and Research Hotspots of Forensic Kinship Testing

Kinship testing is widely needed in forensic science practice. This paper reviews the definitions of common concepts, and summarizes the basic principles, advantages and disadvantages, and application scope of kinship analysis methods, including identity by state (IBS) method, likelihood ratio (LR) method, method of moment (MoM), and identity by descent (IBD) segment method. This paper also discusses the research hotspots of challenging kinship testing, complex kinship testing, forensic genetic genealogy analysis, and non-human biological samples.

FYXZZ-06-04-2024-1196
Fa yi xue za zhi
Research on Logic Design of Proton Treatment Control System

To calculate the likelihood ratios of incest cases using identity by descent (IBD) patterns. The unique IBD pattern was formed by denoting the alleles from the members in a pedigree with a same digital. The probability of each IBD pattern was obtained by multiplying the prior probability by the frequency of non-IBD alleles. The pedigree likelihoods of incest cases under different hypotheses were obtained by summing all IBD pattern probabilities, and the likelihood ratio(LR) was calculated by comparing the likelihoods of different pedigrees. The IBD patterns and the formulae of calculating L

FYXZZ-06-04-2024-1195
Fa yi xue za zhi